Tumor marker

종양표지자(tumor marker, 암표지자)는 보통 선별검사로서의 가치는 떨어지나 재발의 추적, 수술의 성공 여부 등을 판단하는데 이용된다.

종류

• Alpha fetoprotein(AFP): germ cell tumor, hepatocellular carcinoma, hepatoblastoma
• CA15-3: breast cancer
• CA19-9: pancreatic cancer, colorectal cancer, 기타 gastrointestinal cancer
• CA-125: ovarian cancer, endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer, endometriosis
  • endometriosis: 재발의 지표
  • HE4: ovarian cancer
• Carcinoembryonic antigen(CEA): gastrointestinal cancer, cervix cancer, lung cancer, ovarian cancer, breast cancer, urinary tract cancer
  • Colorectal cancer: 재발의 예후인자, 치료효과 판정, 재발 추적
• Prostate-specific antigen(PSA): prostate cancer
• Calcitonin: medullary thyroid carcinoma
• SCC-Ag(Squamous cell carcinoma related antigen): 자궁경부암, 폐암(squamous cell carcinoma)