Drug-induced hypersensitivity syndrome

과민 증후군(hypersensitivity syndrome, Drug-induced hypersensitivity syndrome, DIHS)

임상 양상

• 피부병변+ 혈액, 폐, 간, 콩팥, 심장 등 침범
• 원인 약물: Allopurinol(m/c), Phenytoin, Carbamazepine, Phenobarbital, Sulfasalazine, sulfonamide, Dapsone 등

치료

• Systemic glucocorticoids(prednisone 1 - 2 mg/kg daily) with slow taper over 8- 12 weeks.
• mycophenolate mofetil: rapid recurrence upon steroid taper.

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