"Hypersensitivity reaction"의 두 판 사이의 차이
(새 문서: 분류:Disease 분류:Allergy 과민반응(Hypersensitivity reaction) ==분류== *Type I Immediate type hypersensitivity( IgE depedent or anaphylactic) **ex) Allergic rhnitis...) |
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| 3번째 줄: | 3번째 줄: | ||
==분류== | ==분류== | ||
| + | ===Type 1=== | ||
*Type I Immediate type hypersensitivity( IgE depedent or anaphylactic) | *Type I Immediate type hypersensitivity( IgE depedent or anaphylactic) | ||
| − | **ex) Allergic rhnitis, asthma, systemic anaphylaxis | + | **ex) [[Allergic rhnitis]], [[asthma]], systemic [[anaphylaxis]], Drug allergies([[penicillin]], insulin, cephalosporin) |
| + | |||
| + | ===Type 2=== | ||
*Type IIa Cytotoxic or cytolytic reactions | *Type IIa Cytotoxic or cytolytic reactions | ||
**ex) Drug allergies(penicillin) | **ex) Drug allergies(penicillin) | ||
*Type IIb Cell stimulating reactions involving altered cell function | *Type IIb Cell stimulating reactions involving altered cell function | ||
| − | **ex) Chronic urticaria | + | **ex) Chronic [[urticaria]] |
| + | |||
| + | ===Type 3=== | ||
*Type III Antigen-antibody complex(immune complex) hypersensitivity reaction | *Type III Antigen-antibody complex(immune complex) hypersensitivity reaction | ||
| − | **ex) Serum sickness | + | **ex) [[Serum sickness]] |
| + | |||
| + | ===Type 4=== | ||
*Type IVa1 Classical delayed type | *Type IVa1 Classical delayed type | ||
| − | **ex) Contact dermatitis, tuberculin reaction | + | **ex) [[Contact dermatitis]], tuberculin reaction |
*Type IVa2 Cell mediated eosinophlic(or Chronic allergic inflammation | *Type IVa2 Cell mediated eosinophlic(or Chronic allergic inflammation | ||
**ex) Chronic asthma, chronic allergic rhinitis | **ex) Chronic asthma, chronic allergic rhinitis | ||
2015년 11월 12일 (목) 11:35 판
과민반응(Hypersensitivity reaction)
목차
분류
Type 1
- Type I Immediate type hypersensitivity( IgE depedent or anaphylactic)
- ex) Allergic rhnitis, asthma, systemic anaphylaxis, Drug allergies(penicillin, insulin, cephalosporin)
Type 2
- Type IIa Cytotoxic or cytolytic reactions
- ex) Drug allergies(penicillin)
- Type IIb Cell stimulating reactions involving altered cell function
- ex) Chronic urticaria
Type 3
- Type III Antigen-antibody complex(immune complex) hypersensitivity reaction
- ex) Serum sickness
Type 4
- Type IVa1 Classical delayed type
- ex) Contact dermatitis, tuberculin reaction
- Type IVa2 Cell mediated eosinophlic(or Chronic allergic inflammation
- ex) Chronic asthma, chronic allergic rhinitis
- Type IVb Tissue injury by cytotoxic T cell
- ex) contact dermatitis
IgE Ab crosslink에 의한 mast cell 활성화 기전
- Allergen cross linkage of cell-bound IgE
- Antibody cross-linkage of IgE
- chemical cross linkage of IgE
- cross-linkage of IgE receptors by anti-receptor antibody
- enchanced Ca2+ influx by ionophore that increases membrane permeability to Ca2+
호산구의 Toxic protein
- MBP(Major basic protein)
- ECP(Eosinophil cationic protein)
- EDN(Eosinophil-derived neurotoxin)