Acetylcholinesterase inhibitor

Acetylcholinesterase inhibitor(anti-cholinesterase)는 acetylcholine을 분해하는 acetylcholinesterase enzyme을 불활성화시킨다. 따라서 neurotransmitter인 acetylcholine의 농도와 작용 시간을 늘리는 효과가 있다.

이용

• Alzheimer's disease
• myasthenia gravis
• glaucoma
• postural tachycardia syndrome
• anticholinergic poisoning

Reversible inhibitor

• Carbamates
  • Neostigmine
  • Pyridostigmine
  • Rivastigmine
• Phenanthrene derivatives
  • Galantamine
• Caffeine – noncompetitive (also an Adenosine receptor antagonist)
• Piperidines
  • Donepezil
• Tacrine, also known as tetrahydroaminoacridine