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Paget disease

Jin (토론 | 기여)님의 2021년 3월 30일 (화) 10:46 판

Paget disease(bone Paget's disease, 뼈 파제트병)은 뼈의 재형성이 과도하게 항진되는 질환이다.

Clinical manifestation

  • pelvis(m/c), spine, skull and proximal long bones

Imaging features

  • characteristic radiographic features
    • Lytic phase : osteolysis, particularly affecting the skull (osteoporosis circumscripta) and

subchondral long bones

    • mixed phase : subsequent development of trabecular and cortical thickening and enlargement of bone
    • blastic phase : sclerosis
  • Pelvic bone
    • cortical thickening and sclerosis of the iliopectineal and ischiopubic lines
    • acetabular protrusion
    • enlargement of the pubic rami and ischium