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"Paget disease"의 두 판 사이의 차이

7번째 줄: 7번째 줄:
 
==Imaging features==
 
==Imaging features==
 
*characteristic radiographic features
 
*characteristic radiographic features
**Lytic phase : osteolysis, particularly affecting the skull([[osteoporosis circumscripta]]) and
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**Lytic phase : osteolysis, particularly affecting the skull([[osteoporosis circumscripta]]) and subchondral long bones
subchondral long bones
 
 
**mixed phase : subsequent development of trabecular and cortical thickening and enlargement of bone  
 
**mixed phase : subsequent development of trabecular and cortical thickening and enlargement of bone  
 
**blastic phase : sclerosis
 
**blastic phase : sclerosis

2021년 3월 30일 (화) 10:47 판

Paget disease(bone Paget's disease, 뼈 파제트병)은 Bone remodeling이 과도하게 항진되는 질환이다.

Clinical manifestation

  • pelvis(m/c), spine, skull and proximal long bones

Imaging features

  • characteristic radiographic features
    • Lytic phase : osteolysis, particularly affecting the skull(osteoporosis circumscripta) and subchondral long bones
    • mixed phase : subsequent development of trabecular and cortical thickening and enlargement of bone
    • blastic phase : sclerosis
  • Pelvic bone
    • cortical thickening and sclerosis of the iliopectineal and ischiopubic lines
    • acetabular protrusion
    • enlargement of the pubic rami and ischium